One Gene Therapy 'Change the Paradigm of Cancer Treatment': Might Be the Solution for 'Terminal' Cancer Patients
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Terminal cancer patients finally had a glimpse of hope with the new research made by the US pharmaceutical company. The treatment is known as one gene therapy treatment.
With the help of pharmaceutical giant Kite Pharma, this newest one gene therapy named as CAR-T cell therapy this has been developed. This therapy helped terminal cancer patients to develop blood cells in order to target and combat cancer cells.
This revolutionary one gene therapy treatment resulted from a remarkable outcome of the 36 percent of 101 terminal cancer patients who are in complete remission. In six months of trial, eight in 10 cancer patients witnessed that their cancer shrinks by at least half.
What is extremely promising with this one gene therapy is that in six months later, it could "change the paradigm of cancer treatment" declared by Jeff Wieczorek, senior vice president of clinical development at Kite Pharma. He even described the result as "exceptional" from the improvement they are seeing from the terminal cancer patients.
This one gene therapy works by filtering the blood of terminal cancer patients in order to remove T-Cells, key immune system cell and modify it in a laboratory. Once modified, they will add a gene to T-cells that will help to combat cancer cells. This will allow the immune cells to do their job properly. Martin Ledwick, head nurse at Cancer Research UK suggests that this "CAR-T cell therapy could become a treatment option for some patients with certain types of lymphoma."
However, this one gene therapy comes with a high risk as well. The fact that 101 terminal cancer patients participated in this study, sadly, two of them died from the treatment itself, not with their cancer.
The next step for this one gene therapy is to seek for approval. It will be presented at the American Association for Cancer conference this coming April and from the European regulators. The success of this one will be the success of all terminal cancer patients!